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Home   COVID-19 treatment studies for Melatonin  COVID-19 treatment studies for Melatonin  C19 studies: Melatonin  Melatonin   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Recovery 73% Improvement Relative Risk c19melatonin.com/alizadeh.html Favors melatonin Favors control
29 May 2021 - Early treatment study
A Pilot Study on Controlling Coronavirus Disease 2019 (COVID-19) Inflammation Using Melatonin Supplement
Alizadeh et al., Iranian Journal of Allergy, Asthma and Immunology (Peer Reviewed)
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Small RCT 31 mild/moderate COVID-19 outpatients in Iran, 14 treated with melatonin, showing improved recovery with treatment.
risk of no recovery, 73.0% lower, RR 0.27, p = 0.06, treatment 2 of 14 (14.3%), control 9 of 17 (52.9%), NNT 2.6, day 14. With the observed event rates, ~2 more patients per arm would result in statistical significance.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Alizadeh et al., 5/29/2021, Single Blind Randomized Controlled Trial, Iran, Middle East, peer-reviewed, 6 authors.
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