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All Studies   Meta Analysis   Recent: 
Efficacy of Melatonin in the Treatment of Patients With COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lan et al., Journal of Medical Virology, doi:10.1002/jmv.27595
14 Jan 2022    Source   PDF   Share   Tweet
Systematic review and meta analysis including 3 of the 5 melatonin RCTs at the time, showing significantly higher recovery with treatment, and lower ICU admission and mortality without statistical significance. The analysis only includes trials before 9/11/21. Adding Hasan (October 2021) results in statistically significant lower mortality.
Currently there are 16 melatonin for COVID-19 studies, showing 54% [26‑72%] lower mortality, 31% [4‑50%] lower ventilation, 6% [-4‑15%] lower ICU admission, 54% [-262‑94%] lower hospitalization, and 38% [-6‑64%] lower cases.
Lan et al., 1/14/2022, peer-reviewed, 6 authors.
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